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The study attempts to build a collaborative virtual reality learning system (CVRLS) for medical education.The CVRLSwas designed by using Xj3D and was based upon the imagination, interaction and immersion features of virtual reality (VR) and the benefits of collaborative learning. With the cross-platform feature and networking resources supports from Xj3D, CVRLS establishes a multi-user,cross-platform collaborative virtual learning environment. Under this environment, learners and instructors are able to perform collaborative learning and engage in group discussions regardless of their locations and types of computer systems.